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Savara Announces Encore Presentations of Results from the Phase 3 Clinical Trial of Molgramostim Inhalation Solution (Molgramostim) in Autoimmune Pulmonary Alveolar Proteinosis (APAP) at the European Respiratory Society (ERS) Congress 2026

Business Wire

-- Company to Host Industry Evening Mini-Symposium on aPAP with Renowned Key Opinion Leaders --

YARDLEY, Pa., August 24, 2026--Savara Inc. (Nasdaq: SVRA), a clinical stage biopharmaceutical company focused on rare respiratory diseases, announced the acceptance of one oral presentation and two poster presentations on data from the Phase 3 IMPALA-2 clinical trial at the ERS Congress in Barcelona, Spain, September 5-9, 2026.

"Collectively, these data show that molgramostim continues to improve lung function, exercise capacity, and quality of life in patients, while reductions in biomarkers of aPAP lung disease severity suggest it may normalize the underlying pathobiology," said Bruce C. Trapnell, M.D., Professor of Medicine and Pediatrics at the University of Cincinnati College of Medicine and the Lead Clinical Investigator of the IMPALA-2 clinical trial. "Combined with the high retention rate in the trial and durability of effect we've now seen through the first 48-weeks of the IMPALA-2 open-label period, these results strongly support molgramostim's potential as an effective long-term option for a patient population with no approved pharmacologic treatments. We look forward to sharing these data at the ERS Congress."

Oral Presentation

Title: Molgramostim for the treatment of patients with autoimmune pulmonary alveolar proteinosis (aPAP): long-term efficacy and safety results from the open-label period of the IMPALA-2 phase 3 clinical trial
Presentation Number: OA2381
Session: 3J – Clinical and scientific advances in rare lung diseases
Date/Time: Sunday, September 6, 2026, 3:45 – 5:00 PM CEST
Location: Fira Gran Via (Hall 3)
Presenter: Bruce C. Trapnell, M.D., Professor of Medicine and Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States

Poster Presentations

Title: Molgramostim improves exercise capacity, distance walked, and duration of exercise in patients with autoimmune pulmonary alveolar proteinosis (aPAP): results from the IMPALA-2 Phase 3 clinical trial
Poster Number: PA885
Session: PS-37 – Alveolar-filling disorders and autoimmune lung disease
Date/Time: Sunday, September 6, 2026, 8:00 – 9:30 AM CEST
Location: Fira Gran Via (Hall 1)
Presenter: Cormac McCarthy, M.D., Ph.D., FRCPI, Associate Professor of Medicine, University College Dublin (UCD) and Consultant Respiratory Physician, St. Vincent's University Hospital, Dublin, Ireland

Title: Biomarker levels in patients with autoimmune pulmonary alveolar proteinosis (aPAP): results from the IMPALA-2 phase 3 clinical trial
Poster Number: PA886
Session: PS-37 – Alveolar-filling disorders and autoimmune lung disease
Date/Time: Sunday, September 6, 2026, 8:00 – 9:30 AM CEST
Location: Fira Gran Via (Hall 1)
Presenter: Yoshikazu Inoue, M.D., Ph.D., Executive Director of the Clinical Research Center, NHO Kinki Chuo Chest Medical Center and Internal Medicine, Osaka Anti-Tuberculosis Association Osaka Fukujuji Hospital, Osaka, Japan

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