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- From Phase III Trials to Commercialization Partnerships, MindRank's AI Drug Development Value Comes into FocusHong Kong, Oct 9, 2026 - As AI Drug Development Approaches Commercialization, MindRank Marks a Key Business Milestone How much value can AI create in the discovery and development of new medicines' For investors following the sector, the answer lies in tangible progress in drug development and business execution. A platform’s ability to consistently generate drug candidates, advance lead assets through clinical development and secure recognition from industry partners provides an important basis for assessing an AI drug developer’s growth potential. The recently announced commercialization partnership by MindRank AI Ltd. (MindRank, hereinafter “MindRank”) offers a new window into this question. On September 28, 2026, MindRank announced an exclusive commercialization partnership with 3SBio (01530.HK) subsidiaries Sunshine Mandi and Wansheng Pharmaceutical for MDR-001, its internally developed, AI-designed oral small-molecule GLP-1 receptor agonist. Covering mainland China, Hong Kong and Macau, the agreement carries a potential total transaction value of up to RMB1.75 billion, alongside a substantial share of sales revenue. MDR-001 is currently undergoing a pivotal Phase III clinical trial in China in adults with obesity or overweight. For MindRank, a clinical-stage AI-native drug discovery and development technology company, the partnership further connects drug development with commercialization planning. It lays the groundwork for marketing its lead asset following potential approval and establishes a clearer pathway for translating AI-driven research into commercial value. As its lead asset advances through pivotal clinical development, MindRank has begun preparing for post-approval marketing and channel coverage, extending the product’s development pathway into commercialization. Under the agreement, Sunshine Mandi and Wansheng Pharmaceutical will provide exclusive, comprehensive services and distribution across all channels following MDR-001’s launch. MindRank will retain all rights, title and interests in the product’s intellectual property and remain responsible for clinical development, regulatory submissions, manufacturing and supply. The transaction includes up to RMB150 million in payments for collaboration rights, up to RMB1.6 billion in royalty payments upon the fulfillment of agreed conditions, and a substantial share of sales revenue. From a business-model perspective, the agreement establishes a clear division of responsibilities. MindRank will continue investing in research and product development, while its partners will provide exclusive, comprehensive services and distribution across all channels within the agreed territories following regulatory approval and launch. In an industry that requires sustained investment, this collaboration could help MindRank retain its core asset rights while drawing on its partners’ commercial capabilities to support launch preparations and focus its own resources on strengthening its core capabilities. The partners’ willingness to make commercialization arrangements for an investigational drug also provides a new reference point for assessing its potential industry value. Clinical data address whether a product merits further development, while commercial partnerships indicate whether industry participants are willing to take part in its subsequent development. Together, these elements make MindRank’s growth story more tangible. A Lead Asset in Phase III Provides a Clearer Basis for Assessing AI-Driven R&D Capabilities The core asset underpinning the partnership is MDR-001, which continues to advance through development. In February 2026, MindRank announced that the first participant had been dosed in MOBILE, its Phase III clinical trial of MDR-001. According to the company, the multicenter, randomized, double-blind, placebo-controlled study plans to enroll approximately 750 participants across around 50 clinical centers in China to further evaluate the product’s long-term efficacy and safety. This means the evidence available to assess MindRank’s AI-driven R&D capabilities now extends to larger-scale, late-stage clinical research. For investors, the lead asset’s entry into Phase III sharpens the focus on several key questions: whether long-term efficacy can be further validated, whether safety and tolerability findings can be sustained, and whether the product can establish clinically meaningful competitive advantages. Previously disclosed Phase IIb findings supported further development. In the study, which enrolled 317 adults with obesity or overweight, participants in the MDR-001 dose groups achieved mean reductions in body weight from baseline of 8.2% to 10.3% after 24 weeks, compared with 2.5% in the placebo group. The rate of treatment discontinuation due to treatment-emergent adverse events was 0.8%. Common adverse events were primarily gastrointestinal and mostly mild to moderate. These findings remain subject to further validation in subsequent studies. For weight-management medicines, product value depends on a combination of weight-loss efficacy, long-term safety, tolerability and ease of use. Compared with the injectable peptide-based GLP-1 medicines that currently dominate the market, MDR-001’s oral small-molecule formulation can significantly improve medication adherence, while its large-scale manufacturing costs are substantially lower than those of peptide-based medicines, offering considerable market potential and commercial value. These attributes provide a promising direction for its future product positioning, although translating them into a competitive advantage will require continued accumulation of clinical evidence. Beyond progress in product development, R&D efficiency is another important lens through which to assess MindRank. According to the company, MDR-001 progressed from project initiation to preclinical candidate (PCC) nomination in just eight months, during which approximately 80 small molecules were synthesized. Its investigational new drug (IND) application was cleared in the United States within 19 months of project initiation and MDR-001 advanced to Phase III in China in approximately 4.5 years. In its July 2026 financing announcement, the company further disclosed that cumulative direct R&D investment in the program, from initiation through the start of Phase III in China, totaled approximately US$23 million. These timelines and investment figures provide a more concrete basis for understanding how MindRank organizes drug discovery and development. For drug developers, development timelines and funding requirements directly affect how many programs they can advance, how long they can sustain development and how they allocate resources to subsequent work. AI’s commercial significance must also be assessed within these real-world R&D constraints. As a flagship application of MindRank’s AI-driven drug discovery and development system, MDR-001 offers a traceable development pathway: from molecular design to clinical research and, subsequently, commercialization partnerships. The platform’s capabilities are beginning to be tested through tangible business outcomes. This provides capital markets with a more useful basis for understanding the company’s technology value than descriptions of algorithms or model parameters alone. Beyond the Lead Asset, Long-Term Growth Depends on Sustained Platform Output MDR-001 is the central focus of MindRank’s business progress at this stage, while the company’s long-term growth potential also depends on its ability to continue developing new drug assets. According to the MindRank, its end-to-end AI drug development engine, MAP (Molecule Arts Platform), integrates biology, chemistry, computation, experimental validation and clinical learning into a unified drug discovery and development system. In July 2026, the company announced that it had completed a cumulative US$52 million Series B financing in stages, with proceeds earmarked for further platform development and the advancement of its clinical and preclinical pipeline. In September 2026, the company formally launched Intera (Intelligence Era), its life-sciences foundation model system, and released a technical report on InteraFold-Chem, the first model in the InteraFold series. From an operating perspective, platform development and pipeline advancement have the potential to reinforce each other. R&D programs bring real-world problems and experimental feedback to the platform, while platform iterations support the discovery and optimization of subsequent programs. Ultimately, the platform’s value must be reflected in sustained output: its ability to advance more molecules with development potential across different targets and disease areas, gradually building a business supported by multiple assets. MindRank has already expanded beyond metabolic diseases. In March 2025, the company disclosed that MRANK-106, an oral dual inhibitor of WEE1 and YES1, had received IND approval in the U.S. in oncology. This development provides another case through which to assess the applicability of its AI platform across different R&D areas, although the product’s potential remains subject to subsequent clinical validation. In earlier-stage research, the company disclosed in April 2026 that a collaborative study on drug discovery for Alzheimer’s disease, conducted by MindRank, the University of Macau and Imperial College London, had been published in Nature Biomedical Engineering. The work combined AI screening with experimental validation to identify small molecules meriting further investigation, demonstrating the company’s research capabilities and exploration at the forefront of drug discovery for complex diseases. These programs are at different stages, and their contributions to the company’s value need to be assessed separately. MDR-001 remains the main focus of current clinical development and commercialization preparations, while other pipeline programs and research support the platform’s broader applicability and long-term project portfolio. As more programs deliver verifiable progress, outside observers will be better positioned to assess whether the company can consistently replicate its R&D capabilities. Viewed through this lens, the recent commercialization partnership offers an opportunity to reassess MindRank. Its lead asset has entered pivotal clinical development, partners are participating in commercialization preparations at an early stage, financing supports continued R&D, and its presence across multiple areas preserves opportunities for future growth. These interconnected developments make the company’s development trajectory easier for capital markets to understand. MDR-001 remains in clinical development and has not yet received marketing approval. Its future value realization depends on clinical results, regulatory approval and commercial execution. Nevertheless, the business progress achieved to date provides a more concrete basis for assessing MindRank. For investors following opportunities at the intersection of AI and innovative medicines, the central question worth tracking is whether the company can progressively translate its established R&D capabilities into more verifiable drug assets and commercial outcomes.
- S.A.F.E. Structure DesignsS.A.F.E. Structure Advances U.S. Army Corps of Engineers-Tasked Gallium Recovery Pilot to Strengthen America's Critical Minerals Supply ChainNevada initiative combines American manufacturing, laboratory-proven technology, bipartisan support, and planned workforce education to build domestic critical minerals recovery capacity. — S.A.F.E.StructureDesigns LLC (SAFE), a Nevada-based defense...
- University of Tennessee, Knoxville's Haslam College of Business/C O R R E C T I O N -- University of Tennessee, Knoxville's Haslam College of Business/In the news release, UT Haslam Launches Institute for the Future of Business to Address AI, Tech Changes in Business and Education, issued 07-Oct-2026 by University of Tennessee, Knoxville's Haslam College of Business over PR Newswire, we are advised by the company that changes have been...
- NYU Langone Health SystemHuman Milk Offers a Window Into Mammary Gland Function--and Its Links to Infant GrowthA study led by researchers at NYU Grossman School of Medicine identified shared molecular patterns in human milk that link maternal nutrition, mammary gland biology, and infant growth. Researchers analyzed thousands of molecular measurements from...
- ROKT Pte. Ltd.Rokt Leaders Join Wayne Gretzky and executives from Fanatics, Lowe's, Southwest Airlines and Mastercard to Discuss Leadership, Commerce Media and AI at Advertising Week New York 2026Companies: Lowe'sMastercardSouthwest AirlinesEight sessions across Advertising Week and The Female Quotient Lounge brought Rokt together with leaders from companies including Block, e.l.f. Beauty, American Airlines and FOX One. — Rokt, the leading ecommerce company using machine learning and AI...
- RenaissanceRenaissance Named to 2026 Fortune Best Workplaces in Education & Training ListEdtech leader also earns its fourth consecutive Great Place To Work® Certification™, highlighting its mission-driven, people-first culture — Renaissance, a global leader in pre-K–12 education technology, today announced its dual recognition...
- Newsweek Wins Anti-SLAPP Ruling Against Olivet University, Establishing Entitlement to Attorneys’ FeesNewsweek today announced that the Supreme Court of the State of New York, New York County, has granted summary judgment in its favor on its anti-SLAPP claim against Olivet University, establishing Newsweek’s entitlement to recover attorneys’ fees arising from Olivet’s unsuccessful defamation litigation.
- Center for Creative LeadershipDesign, Customize & Scale Leadership Development Faster: Introducing My Studio™ in CCL Passport™My Studio helps learning teams spend less time building programs and more time developing leaders. — The Center for Creative Leadership® (CCL®) introduces My Studio™, a leadership development workspace powered by AI that helps organizations...
- Eco Expo Asia opens at AsiaWorld-Expo in late OctoberHong Kong, Oct 8, 2026 - Eco Expo Asia 2026, jointly organised by the Hong Kong Trade Development Council (HKTDC) and Messe Frankfurt (HK) Ltd, co-organised by the Environment and Ecology Bureau of the Government of the Hong Kong Special Administrative Region (HKSAR), will be held from 26 to 29 October at AsiaWorld-Expo. HKTDC Associate Executive Director Silas Chu said: "Last month, the Hong Kong SAR Government unveiled the Policy Address and first Five-Year Plan, setting out a vision for building a green and liveable city. Across the region and beyond, China, the European Union and many ASEAN economies are actively pursuing carbon-neutrality or net-zero emission targets, and driving decarbonisation through regulations and industrial policies. Green transformation has shifted from policy aspiration to market rule. As global demand for ESG and green solutions continues to grow, Eco Expo Asia will bring together green technologies, innovative solutions, and global business opportunities to help enterprises capitalise on the new prospects emerging from this transition." HKTDC Associate Executive Director Silas Chu says that Hong Kong's first Five-Year Plan and the latest Policy Address have set out a number of policy directions on environmental protection, underscoring the importance of building a green and liveable city and developing the green energy industry. He adds that this year's Eco Expo Asia will echo current global trends and policy directions, showcasing the latest environmental products and technologies across four thematic areas. He added, "This year's Eco Expo Asia brings together over 340 exhibitors from 16 countries and regions, including first-time participants from Indonesia, Laos, Myanmar, the Philippines, Thailand, and Vietnam, highlighting the Expo’s growing international reach. Some 200 key officials and representatives of semi-official organisations from the Chinese Mainland, Hong Kong, Belt and Road countries, and ASEAN, will attend and tour the Expo, further promoting cross-regional cooperation and exchange." Speaking at the press conference, the Deputy Director of the Environmental Protection Department of the HKSAR Government, Dr Vanessa Au, expressed: "The 21st edition of Eco Expo Asia, held under the theme 'Connecting the World for a Sustainable Future', dovetails with the HKSAR Government's First Five-Year Plan, and implements the Policy Address precisely aligning with the National 15th Five-Year Plan. It underscores our commitment to advancing Hong Kong's green transformation, fostering green innovation, seizing the opportunities presented by the low-carbon economy, creating economic benefits and enhancing citizen well-being. Key highlights of this year's expo include the HKSAR Government booth, the Environmental Campaign Committee Pavilion, the Hong Kong Pavilion and the newly established comprehensive experience zone for green technology. This year during the expo, the Environment and Ecology Bureau and the Ministry of Ecology and Environment of the People's Republic of China will, for the first time, co-host the Belt and Road Green Innovation Conference in Hong Kong. In addition, the Environmental Protection Department, in association with the Belt and Road Initiative International Green Development Coalition and the Chinese Academy of Sciences, will jointly organise the second edition of the 'Green Silk Road' International Training Programme. This expo brings together stakeholders from all sectors, uniting our efforts to advance global carbon neutrality and sustainable development." Silas Chu, HKTDC Associate Executive Director (centre); Dr Vanessa Au, Deputy Director of Environmental Protection (left); and Jack Wong, Deputy General Manager of Messe Frankfurt (HK) Ltd (right), attend today's press conference. Businesses show continued strong confidence in Hong Kong as an ESG business hub The HKTDC has also released the "HKTDC ESG Index 2026". The latest ESG Index stood at 67.3, up from 64.2 last year and well above the neutral threshold of 50, reflecting the continued strengthening of corporate confidence in Hong Kong's role as an ESG hub. The survey also showed that 93% of respondents have integrated ESG into their overall business decision-making processes, while the share of businesses sourcing or selling ESG-related products and services rose from 29% in 2025 to 46% in 2026. Silas said, "The rise in the ESG index reflects the continued strengthening of global businesses' confidence in Hong Kong's role as an ESG business hub. Results further demonstrate that ESG is increasingly being built into business decisions on investment, sourcing, and supply chain management, fuelling steady growth in demand for ESG products, services and solutions. ESG has evolved beyond a compliance requirement into a source of competitive advantage for companies." With strong demand for ESG solutions, Hong Kong is well-positioned to unlock commercial opportunities across banking and finance, professional services, and innovation and technology. In terms of technological innovation, surveyed businesses identified the most impactful Hong Kong digital and ESG platforms for boosting performance as sustainable supply chain platforms (45%), AI analytics (37%), and cloud data reporting (30%). On supply chain management, respondents most valued Hong Kong’s ESG certification services (50%), followed by transparency and traceability tools (41%), and ESG audit and risk analysis solutions (36%). Pavilion line-up expands with ASEAN and Qinghai Pavilion debuts Eco Expo Asia brings together green innovations and technologies from around the world, offering the industry a platform to exchange ideas and explore new business opportunities. This year, the number of participating pavilions has risen to 18, covering a wider spread of regions. On the Chinese Mainland front, Qinghai Province makes its first appearance with a pavilion of its own, joined by the nine Chinese Mainland cities in the Greater Bay Area, Macao, Guangxi, Hunan, Shanghai, and Nanjing in Jiangsu Province. Among the international group pavilions, the headline addition is a new ASEAN Pavilion, featuring 13 green technology companies from eight member countries, including Singapore, Laos, Malaysia, Myanmar, the Philippines, Indonesia, Thailand, and Vietnam. An ASEAN networking reception on the opening day will further strengthen business ties with the region. In addition, Korea Institute of Fusion Energy (KFE), bringing two companies, will showcase their marine environmental technologies and waste gas treatment equipment. The US State of Illinois returns after several years, while Canada, Italy, and the Netherlands maintain their regular presence. Regarding Hong Kong exhibitors, the Hong Kong Science and Technology Parks Corporation once again leads 11 start-ups to the Expo to showcase local green innovation achievements. The Hong Kong Pavilion, supported by the Environmental Protection Department and coordinated by the Federation of Hong Kong Industries, is back with 19 local exhibitors presenting a diverse range of eco-friendly products, technologies and solutions. Rounding off the home-grown line-up, the HKSAR Government booth, featuring 11 bureaux and departments including the Environment and Ecology Bureau, and the Environmental Campaign Committee Pavilion, will highlight the city's latest work in environmental protection and green development. The Hong Kong Science and Technology Parks Corporation will lead 11 start-ups to participate in the Expo, including CNAE China Company Limited, which showcases a high-speed electric bike powered by sodium battery. As a member of the HKSAR Government’s GoGlobal Task Force, the HKTDC will set up a GoGlobal Connect Zone, helping Chinese Mainland environmental enterprises tap international markets through Hong Kong's professional services. A seminar on going global rounds out the programme, sharing practical experiences in expanding overseas. Four thematic areas spotlight green innovation Aligned with global trends and policy directions, this year's Expo centres on four areas: Green Energy in Motion, Frontier Green Tech, Building for a Greener City and From Waste to Worth, showcasing the latest innovative green technologies, products, and solutions. Under "Green Energy in Motion", the Expo features green energy solutions spanning the maritime, land transport and aviation sectors. Echoing the call in the Policy Address and Hong Kong's First Five-Year Plan to build a Sustainable Aviation Fuel (SAF) industry chain, EcoCeres Ltd. (Booth: 3-F30), a global leading SAF producer, makes its Expo debut with its advanced renewable SAF made from waste materials, alongside Hydrotreated Vegetable Oil (HVO). The Hong Kong Science and Technology Parks Pavilion (Booth: 3-E02) will also focus on energy, with start-ups presenting innovations such as EV chargers and modular EV conversion technology. EcoCeres Ltd. showcases Sustainable Aviation Fuel (SAF) and Hydrotreated Vegetable Oil (HVO), two advanced renewable fuels made from waste-based feedstocks. Under the "Frontier Green Tech" theme, around 30 start-ups and university spin-offs will show how research achievements have been transformed into practical environmental applications. Among them, first-time exhibitor Stellerus Technology Limited (Booth: 6-D27) will display the Multi-Spectral Imaging Carbon Observatory (MUSICO), the world's first lightweight, high-resolution, high-precision synergistic greenhouse gases observatory, which has already been deployed on China's Tiangong space station. MUSICO monitors greenhouse gas emissions, supporting enterprises in formulating emission-reduction measures and supplying precise data to green finance institutions. First-time exhibitor Stellerus Technology Limited showcases Multi Spectral Imaging Carbon Observatory (MUSICO), which has already been deployed on China's Tiangong space station. The data collected supports corporate carbon reduction measures and provides precise reference metrics for green finance institutions. In keeping with the "building a green and liveable city" policy direction under Hong Kong's Five-Year Plan, the "Building for a Greener City" theme gathers a host of innovations now in real-world use. Green Vigor Limited (Booth: 3-E02) will exhibit a modular hydropower system that converts wasted hydraulic resources from water tanks and cooling systems in buildings into electricity, a solution already in use in local shopping malls, commercial buildings and schools. AEC GreenTech Innovations Limited (Booth: 3-C20) brings a robot designed for plastering and paint spraying, which works at least five times faster than manual labour while halving material use, delivering environmental benefits. The technology has been adopted in local construction projects. Green Vigor Limited brings a modular hydropower system that converts wasted hydraulic resources from the buildings into valuable electricity. The fourth area, "From Waste to Worth", assembles a number of leading Chinese Mainland enterprises in the waste management sector, including Chongqing Sanfeng Environment Group (Booth: 3-E30), named among Top 50 Environmental Enterprises in China and the Top 10 Influential Enterprises in China's Solid Waste Industry, as well as listed environmental companies Dynagreen Environmental Protection Group (Booth: 3-B30) and Beijing Enterprises Environment Group (Booth: 3-D30), showcasing their waste management and resource circular solutions. Hong Kong-based Green AI Technology Limited (Booth: 3-E26) will launch REV, its new generation of the unmanned recycling station at the Expo, demonstrating how AI and automation can be applied to recycling. Green AI Technology Limited will launch REV, a new-generation unmanned recycling station, at the Expo this year, using the latest AI to automatically verify whether recyclables have been correctly sorted. Lingnan University showcases a fleet management system that uses AIoT and GeoAI technology to predict traffic congestion and accident risks in real time. Over 30 key events to gather experts from government, industry, academia and research More than 30 forums and seminars will be held during the Expo, bringing together over 80 government officials, industry leaders and business representatives from the Chinese Mainland, Australia, Malaysia, Thailand, and other Belt and Road countries to share insights on green opportunities, success stories and forward-looking strategies. The annual flagship event, Eco Asia Conference, will also feature a series of seminars centred on four key themes, with industry and academic experts presenting the latest developments. On 26 October, Professor Su Hui, Chair Professor in the Department of Civil and Environmental Engineering at HKUST, who spearheaded the development of MUSICO, will join Professor Kenneth Leung, Director of the State Key Laboratory of Marine Environmental Health at CityUHK, to discuss technologies for monitoring extreme weather and explore Hong Kong's role as a regional green innovation hub. On 27 October, representatives from the Construction Industry Council and China State Construction Engineering (Hong Kong) Ltd will examine green building development from the perspectives of policy, certification and practice. On 28 October, Avinash Persaud, Special Advisor on Climate Change to the President of the Inter-American Development Bank (IDB) and a member of the High-Level Expert Group on Climate Finance for the COP26, 27 and 28 Presidencies, will take to the stage. Drawing on his extensive experience spanning international finance, public policy, and climate finance, he will analyse emerging global trends in the field. Public Day invites everyone to embrace green lifestyles The final day of the Expo (29 October) will be Public Day, with free admission for the public, aiming to raise awareness of environmental protection and sustainability and to encourage the adoption of green lifestyles. A series of seminars on climate, environmental protection and food waste upcycling will be held that day. Speakers include representatives from the Hong Kong Observatory, Hong Kong meteorologist and former Assistant Director of the Hong Kong Observatory Leung Wing Mo, and guests from Ways Out HK, a local social enterprise that turns food waste into jewellery. Visitors can also take part in interactive workshops, including a recycled paper making workshop, green cleaners making workshop and green mini games, enabling participants to learn hands-on how to put resource recycling and green living into practice. Alongside Eco Expo Asia, the HKTDC is holding four major tech fairs this month: the Hong Kong Electronics Fair (Autumn Edition) and electronicAsia, from 13 to 16 October at the Hong Kong Convention and Exhibition Centre in Wan Chai; the Hong Kong International Outdoor and Tech Light Expo, running concurrently with Eco Expo Asia at AsiaWorld-Expo; and the Hong Kong International Lighting Fair (Autumn Edition), to be held from 27 to 30 October. Together, the five fairs will create synergies, fostering cross-sector exchange and business collaboration. Free shuttle bus services will connect the fair venues, major hotels and transport interchanges. For details, please visit: https://www.hktdc.com/event/ecoexpoasia/tc/travel-to-fairground-awe. Website: Eco Expo Asia – https://www.hktdc.com/event/ecoexpoasia/enHKTDC ESG Index 2026 – https://research.hktdc.com/en/article/MjQ0ODY3NzQwMg Photo Download: https://bit.ly/4jbQXeK Media enquiries: For enquiries, please contact: HKTDC Communication and Public Affairs Department: Christy Lee Tel: (852) 2584 4369 Email: [email protected] Dawn Yuen Tel: (852) 2584 4575 Email: [email protected] Jane Cheung Tel: (852) 2584 4137 Email: [email protected] HKTDC Mediaroom: https://mediaroom.hktdc.com/ About HKTDCThe Hong Kong Trade Development Council (HKTDC) celebrates its 60th anniversary this year. The HKTDC is a statutory body established in 1966 to promote, assist and develop Hong Kong's trade. With over 50 offices globally, including 13 in the Chinese Mainland, the HKTDC promotes Hong Kong as a two-way global investment and business hub. The HKTDC organises international exhibitions, conferences and business missions to create business opportunities for companies, particularly small and medium-sized enterprises (SMEs), in the mainland and international markets. The HKTDC also provides up-to-date market insights and product information via research reports and digital news channels. For more information, please visit: www.hktdc.com/aboutus. Follow us on @hktdc and LinkedIn
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