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- THE ROSEN LAW FIRM, P. A.Rosen Law Firm Encourages America's Car-Mart, Inc. Investors to Inquire About Securities Class Action Investigation - CRMTRosen Law Firm, a global investor rights law firm, continues to investigate potential securities claims on behalf of shareholders of America's Car-Mart, Inc. (NASDAQ: CRMT) resulting from allegations that America's Car-Mart may have issued...
- Cedar Electronics selects TomTom Orbis Maps to enhance speed awareness across the United StatesTomTom (TOM2), the specialist in mapping and location technology, today announced that Cedar Electronics, a leading provider of automotive safety and driver awareness solutions, has selected TomTom Orbis Maps for integration into its Escort and Cobra radar detector products in markets where these features are supported.
- Everest Medicines Reports 1H 2026 Results, Enters New Phase as Growth Accelerates and Innovation Gains MomentumEverest Medicines (01952.HK) announced its interim results for the six months ended June 30, 2026. Everest delivered strong growth and reached an important profitability milestone in the first half of 2026. Total revenue increased 157% year-on-year to RMB 1.148 billion, driven by continued commercial momentum across the company’s portfolio. Gross margin excluding non-cash items reached 73.7%, while operating expenses as a percentage of revenue decreased by 64.0 percentage points year-on-year, reflecting increasing operating leverage and execution efficiency. From the first-half results, the company’s growth drivers are broadening beyond the commercialization of core products to include portfolio expansion, monetization of innovative assets, and global expansion. In the first half of 2026, the company achieved non-IFRS net profit of RMB 97.23 million, while IFRS net loss narrowed by 98% year-on-year. Everest ended the period with RMB 1.859 billion in cash. Following the reporting period, the company received approximately RMB 770 million in July from the upfront payment under its global licensing and collaboration agreement for civorebrutinib, further strengthening its financial position and capacity to invest in future growth. Mr. Yifang Wu, Chairman of the Board of Everest Medicines, said: “Everest Medicines has entered a new phase of development as an innovation-driven, integrated biopharmaceutical company. Guided by our 2030 Strategy, we are strengthening our capabilities in innovation, commercialization, and global development, accelerating the realization of global value and laying a stronger foundation for sustainable, high-quality growth.” During the period, the company achieved profitability, while expanding its innovative pipeline and advancing its R&D programs. Through continued efforts to strengthen its BD capabilities, the company is developing a model that combines in-licensed and internally developed early-stage assets, exemplified by civorebrutinib (also known as EVER001), with internal incubation and development creating opportunities to out-license innovative assets and realize their value. At the same time, the company is bringing in high-quality mid- to late-stage assets, exemplified by NEFECON(R), while continuing to build its commercialization capabilities and generate further opportunities for BD partnerships. These efforts are enhancing the efficiency of innovation resource allocation and accelerating the translation of innovation into clinical and commercial value. Everest’s marketed portfolio continued to gain momentum NEFECON(R) maintained strong sales momentum. In the first half of 2026, sales revenue from NEFECON(R) reached RMB 889 million, with net sales increasing 94% year-on-year. Through deeper penetration across key hospitals, broader market expansion, enhanced physician and patient education, and continued generation of real-world evidence, Everest is supporting broader adoption of treatment strategies focused on addressing underlying causes, early intervention, and long-term management. Following approval, VELSIPITY(R) moved rapidly into commercialization, with local manufacturing progressing. XERAVA(R) delivered steady hospital sales growth, while local manufacturing advanced as planned. The company also reached an understanding with Hainan Herui Pharmaceutical Co., Ltd. regarding certain NEFECON(R)-related patent matters and entered into a commercialization collaboration for budesonide enteric capsules, further broadening treatment options for patients. Meanwhile, commercialization services for Hasten Biopharmaceuticals continued to contribute to revenue growth. Services for mature products under the CSO arrangement commenced in March 2026, generating RMB 145 million in service revenue and RMB 28 million in commercialization profit in the first half of the year. Mr. Rogers Yongqing Luo, Chief Executive Officer of Everest Medicines, said: “In the first half of 2026, the company continued to execute its strategy and accelerate the translation of innovation into clinical and commercial value. Solid progress across commercialization, BD, in-house R&D, and global expansion further strengthened our foundation for sustainable growth and our ability to bring innovative therapies to patients. Our BD strategy is building a diversified portfolio of future growth drivers through global partnerships for internally developed assets and selective in-licensing of differentiated innovative assets, while our in-house R&D continues to generate clinical progress. With the establishment of a pan-Asia-Pacific commercialization platform, we are also extending our proven capabilities from China into other Asian markets.” EVER001 global licensing deal expected to accelerate overseas development In June, the company entered into an exclusive licensing and collaboration agreement with Travere Therapeutics, Inc. (NASDAQ: TVTX) for the development and commercialization of civorebrutinib (also known as EVER001) in all markets outside China and certain countries in East and Southeast Asia. The deal has a total potential value of up to $1.1425 billion, including an upfront payment of $112.5 million and up to approximately $1.03 billion in additional cash payments tied to specified clinical development, regulatory and commercial milestones across up to five indications. Travere will also pay tiered royalties on future sales in its licensed territories, ranging from high single-digit to double-digit percentages based on annual net sales thresholds. CICC believes the partnership is expected to accelerate the global clinical development and commercialization of EVER001 and could advance its development in membranous nephropathy. BOCOM International is positive on EVER001’s overseas market potential and its development opportunities across additional indications. EVER001 achieved positive 52-week Phase 1b/2a clinical results, and a Phase 2 basket trial has been initiated in China to further evaluate its potential in autoimmune kidney diseases, including FSGS, MCD, and IgAN. BD expansion further strengthens the product pipeline The company continued to selectively introduce mid- to late-stage assets with strong commercial potential. MT1013, DMX-200, and Bejescin(R) strengthened its nephrology and autoimmune portfolio; CARDAMYST(R) and Sumecigrel (formerly known as Vicagrel) further expanded its cardiovascular portfolio; and LNZ100, together with VIS-101, enhanced its ophthalmology portfolio. With multiple assets moving through key regulatory and commercialization milestones, the company is building a diversified portfolio of future growth drivers. CARDAMYST(R) is expected to receive approval in the third quarter of 2026, LEROCHOL(R) and LNZ100 are expected to receive approval in 2027, and MT1013 is expected to receive approval in 2028. In-house R&D and pan-Asia-Pacific expansion advance The company’s in-house R&D also translated into clinical progress. The company’s proprietary AI+mRNA platform also advanced, with its personalized mRNA cancer vaccine EVM16 achieving its first-in-human clinical data readout and planned to enter an investigator-initiated Phase 1b study in the fourth quarter of 2026. EVM18, the company’s in vivo CAR-T therapy, has initiated IIT studies across multiple autoimmune diseases and is advancing toward global IND filings. The acquisition of Hasten Biopharmaceuticals (SG) Pte. Ltd. further strengthened the company’s global commercialization capabilities and established a pan-Asia-Pacific commercialization platform. The platform provides a foundation for scaling the company’s proven commercialization capabilities from China across Asian markets, supporting the regional expansion of both existing and future products. Meanwhile, CBC Group and the company’s Directors have collectively purchased 5.163 million shares since December 2025, with the transactions totaling more than HK$172.5 million, demonstrating their confidence in the company’s strategic direction and long-term prospects. Overall, Everest Medicines is gradually developing a growth model built on the commercialization of core products, portfolio expansion through BD, a pipeline of innovative assets generated through in-house R&D, and international expansion through global partnerships and its pan-Asia-Pacific platform. As the company enters its new phase, the coordinated strengthening of its capabilities in innovation resource integration, commercialization, and global development is expected to provide an important foundation for future growth.
- 雲頂新耀2026年上半年經營質量持續提升 邁入「3.0階段」加速釋放創新價值香港, 2026年8月19日 - 雲頂新耀（01952.HK）公佈截至2026年6月30日的中期業績報告。中報顯示，2026年上半年，公司經營質量持續提升，總收入達人民幣11.48億元，同比增長157%；剔除非現金項目後毛利率達73.7%，非國際財務准則下實現淨利潤人民幣9,723萬元，國際財務報告准則下淨虧損同比收窄98%；運營費用占收入比重同比下降64.0個百分點，反映公司運營效率和執行效率的持續提升。 從本期表現來看，公司增長動力正由核心產品商業化進一步向產品組合擴容、創新資產價值變現及全球化布局延伸。 截至2026年6月30日，公司現金儲備充裕，達人民幣18.59億元；報告期後，公司於2026年7月收到希布替尼（EVER001）全球授權許可及合作協議項下的人民幣7.7億元首付款，現金餘額進一步充實。公司整體資金實力的繼續增強，為公司後續研發投入及業務拓展提供有力支持。 雲頂新耀董事會主席吳以芳表示：「2026年上半年，雲頂新耀正式邁入3.0階段，成為創新驅動的綜合性生物制藥公司。在2030戰略指導下，公司持續提升創新資源整合能力、商業化運營能力和全球化發展能力，加速創新價值釋放，為長期高質量發展奠定更加堅實的基礎。」 上半年，公司經營質量持續提升，實現扭虧為盈；創新產品管線不斷豐富，研發成果持續積累，臨床價值進一步提升。同時，通過持續強化「雙向」BD能力，公司正逐步形成以希布替尼（EVER001）為代表的「引進+自研」早期資產，通過內部孵化培育實現對外許可的創新資產價值變現模式，以及以耐賦康(R)為代表，通過引入中後期優質管線、持續提升商業化能力，進一步助力更多BD合作的正反饋，持續提升創新資源配置效率，加快推動創新成果向臨床價值和商業價值轉化。 核心產品持續釋放增長潛力 商業化方面，耐賦康(R)銷售收入保持強勁增長。2026年上半年，耐賦康(R)銷售收入達人民幣8.89億元，純銷同比增長94%。公司持續深耕核心醫院網絡，拓展非核心市場覆蓋，加強醫生及患者教育，積累真實世界證據，推動「對因治療、盡早治療、長期治療」診療策略加速落地。維適平(R)獲批後快速實現商業化落地，本地化生產建設持續推進。依嘉(R)院端銷量保持穩健增長，臨床需求持續強勁，但受海外供應鏈影響，產品供應階段性趨緊，公司正有序推進本地化生產，全力保障產品供應及醫保談判相關工作。與此同時，海森生物商業化服務合作穩步推進，貢獻銷售收入。公司與海南合瑞就耐賦康(R)相關專利達成諒解，並開展布地奈德腸溶膠囊商業化合作，進一步拓展患者的用藥選擇。 同時，海森生物商業化服務合作穩步推進，其中成熟產品CSO服務已於2026年3月正式啟動，上半年實現服務收入人民幣1.45億元、商業化利潤人民幣2,800萬元，進一步貢獻收入和利潤。 雲頂新耀首席執行官羅永慶表示：「2026年上半年，公司圍繞既定戰略，加快推動創新成果轉化，商業化、BD、自主研發和全球化布局協同推進，經營質量持續改善，增長動能進一步增強。 在BD和自主研發方面，公司持續推進創新資產的全球合作與優質創新資產引進，自主研發及創新技術平台也持續取得臨床進展，進一步豐富未來增長動力。與此同時，隨著泛亞太商業化平台的建立，公司進一步將中國市場驗證的商業化能力複制至亞洲市場，推動現有及未來產品拓展亞洲市場。」 EVER001全球授權，海外開發有望提速 6月，公司與Travere Therapeutics就希布替尼（EVER001）達成獨家授權許可與合作協議，授予其除大中華區及部分東南亞國家以外區域的獨家開發及商業化權益。根據協議，交易總額高達11.425億美元，其中包括1.125億美元首付款及高達10.3億美元的開發、注冊及商業化里程碑付款，公司同時有望獲得未來淨銷售額高個位數至雙位數百分比的銷售分成。 中金公司認為，該合作將加速EVER001全球臨床開發和商業化進程，並有望推動膜性腎病領域開發。交銀國際看好EVER001的海外市場容量和適應症開發前景，並指出其治療膜性腎病的Ib/IIa期研究52周數據表現積極，海外開發有望提速。基於相關臨床進展，公司已在中國啟動II期籃式試驗，進一步探索其在局灶節段性腎小球硬化（FSGS）、微小病變腎病（MCD）和IgA腎病等自身免疫性腎髒疾病中的治療潛力。 BD持續擴充，產品梯隊進一步完善 在引進方面，公司聚焦核心治療領域和中後期資產，持續完善產品組合：在腎科及自身免疫領域引入MT1013、DMX-200和倍捷欣(R)；心血管領域引入星必妥(R)和維卡格雷，進一步完善心血管產品組合；在眼科領域引入LNZ100，與VIS-101共同強化眼科布局。 隨著多項資產進入關鍵注冊及商業化階段，公司未來產品增長梯隊進一步清晰，其中，星必妥(R)預計2026年第三季度獲批上市，樂瑞泊(R)和LNZ100預計於2027年獲批上市，MT1013有望於2028年獲批上市。 自研及泛亞太布局持續推進 研發方面，自研AI+mRNA平台持續取得突破，個性化腫瘤疫苗EVM16完成首次人體臨床數據讀出，並計劃於2026年第四季度啟動IIT Ib期臨床研究；自體生成CAR-T療法EVM18已啟動針對多類自身免疫疾病的IIT研究，並穩步推進全球IND申報。 全球化方面，公司完成對海森生物制藥（新加坡）的收購，獲得泛亞太商業化平台，加快將中國市場驗證的商業化能力複制至亞洲市場，推動現有及未來產品拓展亞洲市場，進一步提升全球商業化能力。 與此同時，自2025年12月以來，康橋資本及公司董事累計增持516.3萬股，交易金額超1.725億港元，體現了對公司戰略方向和長期發展的信心。 整體來看，雲頂新耀正逐步形成以核心產品商業化為基礎、以BD擴充產品組合、以自主研發儲備創新資產、以全球合作和泛亞太平台拓展國際市場的發展結構。進入「3.0階段」後，創新資源整合、商業化運營和全球化發展能力的協同提升，或將成為公司後續增長的重要支撐。
- 云顶新耀2026年上半年经营质量持续提升 迈入“3.0阶段”加速释放创新价值香港, 2026年8月19日 - (亚太商讯) - 云顶新耀（01952.HK）公布截至2026年6月30日的中期业绩报告。中报显示，2026年上半年，公司经营质量持续提升，总收入达人民币11.48亿元，同比增长157%；剔除非现金项目后毛利率达73.7%，非国际财务准则下实现净利润人民币9,723万元，国际财务报告准则下净亏损同比收窄98%；运营费用占收入比重同比下降64.0个百分点，反映公司运营效率和执行效率的持续提升。 从本期表现来看，公司增长动力正由核心产品商业化进一步向产品组合扩容、创新资产价值变现及全球化布局延伸。 截至2026年6月30日，公司现金储备充裕，达人民币18.59亿元；报告期后，公司于2026年7月收到希布替尼（EVER001）全球授权许可及合作协议项下的人民币7.7亿元首付款，现金余额进一步充实。公司整体资金实力的继续增强，为公司后续研发投入及业务拓展提供有力支持。 云顶新耀董事会主席吴以芳表示：“2026年上半年，云顶新耀正式迈入3.0阶段，成为创新驱动的综合性生物制药公司。在2030战略指导下，公司持续提升创新资源整合能力、商业化运营能力和全球化发展能力，加速创新价值释放，为长期高质量发展奠定更加坚实的基础。” 上半年，公司经营质量持续提升，实现扭亏为盈；创新产品管线不断丰富，研发成果持续积累，临床价值进一步提升。同时，通过持续强化“双向”BD能力，公司正逐步形成以希布替尼（EVER001）为代表的“引进+自研”早期资产，通过内部孵化培育实现对外许可的创新资产价值变现模式，以及以耐赋康(R)为代表，通过引入中后期优质管线、持续提升商业化能力，进一步助力更多BD合作的正反馈，持续提升创新资源配置效率，加快推动创新成果向临床价值和商业价值转化。 核心产品持续释放增长潜力 商业化方面，耐赋康(R)销售收入保持强劲增长。2026年上半年，耐赋康(R)销售收入达人民币8.89亿元，纯销同比增长94%。公司持续深耕核心医院网络，拓展非核心市场覆盖，加强医生及患者教育，积累真实世界证据，推动“对因治疗、尽早治疗、长期治疗”诊疗策略加速落地。维适平(R)获批后快速实现商业化落地，本地化生产建设持续推进。依嘉(R)院端销量保持稳健增长，临床需求持续强劲，但受海外供应链影响，产品供应阶段性趋紧，公司正有序推进本地化生产，全力保障产品供应及医保谈判相关工作。与此同时，海森生物商业化服务合作稳步推进，贡献销售收入。公司与海南合瑞就耐赋康(R)相关专利达成谅解，并开展布地奈德肠溶胶囊商业化合作，进一步拓展患者的用药选择。 同时，海森生物商业化服务合作稳步推进，其中成熟产品CSO服务已于2026年3月正式启动，上半年实现服务收入人民币1.45亿元、商业化利润人民币2,800万元，进一步贡献收入和利润。 云顶新耀首席执行官罗永庆表示：“2026年上半年，公司围绕既定战略，加快推动创新成果转化，商业化、BD、自主研发和全球化布局协同推进，经营质量持续改善，增长动能进一步增强。 在BD和自主研发方面，公司持续推进创新资产的全球合作与优质创新资产引进，自主研发及创新技术平台也持续取得临床进展，进一步丰富未来增长动力。与此同时，随着泛亚太商业化平台的建立，公司进一步将中国市场验证的商业化能力复制至亚洲市场，推动现有及未来产品拓展亚洲市场。” EVER001全球授权，海外开发有望提速 6月，公司与Travere Therapeutics就希布替尼（EVER001）达成独家授权许可与合作协议，授予其除大中华区及部分东南亚国家以外区域的独家开发及商业化权益。根据协议，交易总额高达11.425亿美元，其中包括1.125亿美元首付款及高达10.3亿美元的开发、注册及商业化里程碑付款，公司同时有望获得未来净销售额高个位数至双位数百分比的销售分成。 中金公司认为，该合作将加速EVER001全球临床开发和商业化进程，并有望推动膜性肾病领域开发。交银国际看好EVER001的海外市场容量和适应症开发前景，并指出其治疗膜性肾病的Ib/IIa期研究52周数据表现积极，海外开发有望提速。基于相关临床进展，公司已在中国启动II期篮式试验，进一步探索其在局灶节段性肾小球硬化（FSGS）、微小病变肾病（MCD）和IgA肾病等自身免疫性肾脏疾病中的治疗潜力。 BD持续扩充，产品梯队进一步完善 在引进方面，公司聚焦核心治疗领域和中后期资产，持续完善产品组合：在肾科及自身免疫领域引入MT1013、DMX-200和倍捷欣(R)；心血管领域引入星必妥(R)和维卡格雷，进一步完善心血管产品组合；在眼科领域引入LNZ100，与VIS-101共同强化眼科布局。 随着多项资产进入关键注册及商业化阶段，公司未来产品增长梯队进一步清晰，其中，星必妥(R)预计2026年第三季度获批上市，乐瑞泊(R)和LNZ100预计于2027年获批上市，MT1013有望于2028年获批上市。 自研及泛亚太布局持续推进 研发方面，自研AI+mRNA平台持续取得突破，个性化肿瘤疫苗EVM16完成首次人体临床数据读出，并计划于2026年第四季度启动IIT Ib期临床研究；自体生成CAR-T疗法EVM18已启动针对多类自身免疫疾病的IIT研究，并稳步推进全球IND申报。 全球化方面，公司完成对海森生物制药（新加坡）的收购，获得泛亚太商业化平台，加快将中国市场验证的商业化能力复制至亚洲市场，推动现有及未来产品拓展亚洲市场，进一步提升全球商业化能力。 与此同时，自2025年12月以来，康桥资本及公司董事累计增持516.3万股，交易金额超1.725亿港元，体现了对公司战略方向和长期发展的信心。 整体来看，云顶新耀正逐步形成以核心产品商业化为基础、以BD扩充产品组合、以自主研发储备创新资产、以全球合作和泛亚太平台拓展国际市场的发展结构。进入“3.0阶段”后，创新资源整合、商业化运营和全球化发展能力的协同提升，或将成为公司后续增长的重要支撑。 Copyright 2026 亚太商讯. All rights reserved. www.acnnewswire.com
- Everest Medicines Reports 1H 2026 Results, Enters New Phase as Growth Accelerates and Innovation Gains MomentumEverest Medicines (01952.HK) announced its interim results for the six months ended June 30, 2026. Everest delivered strong growth and reached an important profitability milestone in the first half of 2026. Total revenue increased 157% year-on-year to RMB 1.148 billion, driven by continued commercial momentum across the company’s portfolio. Gross margin excluding non-cash items reached 73.7%, while operating expenses as a percentage of revenue decreased by 64.0 percentage points year-on-year, reflecting increasing operating leverage and execution efficiency. From the first-half results, the company’s growth drivers are broadening beyond the commercialization of core products to include portfolio expansion, monetization of innovative assets, and global expansion. In the first half of 2026, the company achieved non-IFRS net profit of RMB 97.23 million, while IFRS net loss narrowed by 98% year-on-year. Everest ended the period with RMB 1.859 billion in cash. Following the reporting period, the company received approximately RMB 770 million in July from the upfront payment under its global licensing and collaboration agreement for civorebrutinib, further strengthening its financial position and capacity to invest in future growth. Mr. Yifang Wu, Chairman of the Board of Everest Medicines, said: “Everest Medicines has entered a new phase of development as an innovation-driven, integrated biopharmaceutical company. Guided by our 2030 Strategy, we are strengthening our capabilities in innovation, commercialization, and global development, accelerating the realization of global value and laying a stronger foundation for sustainable, high-quality growth.” During the period, the company achieved profitability, while expanding its innovative pipeline and advancing its R&D programs. Through continued efforts to strengthen its BD capabilities, the company is developing a model that combines in-licensed and internally developed early-stage assets, exemplified by civorebrutinib (also known as EVER001), with internal incubation and development creating opportunities to out-license innovative assets and realize their value. At the same time, the company is bringing in high-quality mid- to late-stage assets, exemplified by NEFECON(R), while continuing to build its commercialization capabilities and generate further opportunities for BD partnerships. These efforts are enhancing the efficiency of innovation resource allocation and accelerating the translation of innovation into clinical and commercial value. Everest’s marketed portfolio continued to gain momentum NEFECON(R) maintained strong sales momentum. In the first half of 2026, sales revenue from NEFECON(R) reached RMB 889 million, with net sales increasing 94% year-on-year. Through deeper penetration across key hospitals, broader market expansion, enhanced physician and patient education, and continued generation of real-world evidence, Everest is supporting broader adoption of treatment strategies focused on addressing underlying causes, early intervention, and long-term management. Following approval, VELSIPITY(R) moved rapidly into commercialization, with local manufacturing progressing. XERAVA(R) delivered steady hospital sales growth, while local manufacturing advanced as planned. The company also reached an understanding with Hainan Herui Pharmaceutical Co., Ltd. regarding certain NEFECON(R)-related patent matters and entered into a commercialization collaboration for budesonide enteric capsules, further broadening treatment options for patients. Meanwhile, commercialization services for Hasten Biopharmaceuticals continued to contribute to revenue growth. Services for mature products under the CSO arrangement commenced in March 2026, generating RMB 145 million in service revenue and RMB 28 million in commercialization profit in the first half of the year. Mr. Rogers Yongqing Luo, Chief Executive Officer of Everest Medicines, said: “In the first half of 2026, the company continued to execute its strategy and accelerate the translation of innovation into clinical and commercial value. Solid progress across commercialization, BD, in-house R&D, and global expansion further strengthened our foundation for sustainable growth and our ability to bring innovative therapies to patients. Our BD strategy is building a diversified portfolio of future growth drivers through global partnerships for internally developed assets and selective in-licensing of differentiated innovative assets, while our in-house R&D continues to generate clinical progress. With the establishment of a pan-Asia-Pacific commercialization platform, we are also extending our proven capabilities from China into other Asian markets.” EVER001 global licensing deal expected to accelerate overseas development In June, the company entered into an exclusive licensing and collaboration agreement with Travere Therapeutics, Inc. (NASDAQ: TVTX) for the development and commercialization of civorebrutinib (also known as EVER001) in all markets outside China and certain countries in East and Southeast Asia. The deal has a total potential value of up to $1.1425 billion, including an upfront payment of $112.5 million and up to approximately $1.03 billion in additional cash payments tied to specified clinical development, regulatory and commercial milestones across up to five indications. Travere will also pay tiered royalties on future sales in its licensed territories, ranging from high single-digit to double-digit percentages based on annual net sales thresholds. CICC believes the partnership is expected to accelerate the global clinical development and commercialization of EVER001 and could advance its development in membranous nephropathy. BOCOM International is positive on EVER001’s overseas market potential and its development opportunities across additional indications. EVER001 achieved positive 52-week Phase 1b/2a clinical results, and a Phase 2 basket trial has been initiated in China to further evaluate its potential in autoimmune kidney diseases, including FSGS, MCD, and IgAN. BD expansion further strengthens the product pipeline The company continued to selectively introduce mid- to late-stage assets with strong commercial potential. MT1013, DMX-200, and Bejescin(R) strengthened its nephrology and autoimmune portfolio; CARDAMYST(R) and Sumecigrel (formerly known as Vicagrel) further expanded its cardiovascular portfolio; and LNZ100, together with VIS-101, enhanced its ophthalmology portfolio. With multiple assets moving through key regulatory and commercialization milestones, the company is building a diversified portfolio of future growth drivers. CARDAMYST(R) is expected to receive approval in the third quarter of 2026, LEROCHOL(R) and LNZ100 are expected to receive approval in 2027, and MT1013 is expected to receive approval in 2028. In-house R&D and pan-Asia-Pacific expansion advance The company’s in-house R&D also translated into clinical progress. The company’s proprietary AI+mRNA platform also advanced, with its personalized mRNA cancer vaccine EVM16 achieving its first-in-human clinical data readout and planned to enter an investigator-initiated Phase 1b study in the fourth quarter of 2026. EVM18, the company’s in vivo CAR-T therapy, has initiated IIT studies across multiple autoimmune diseases and is advancing toward global IND filings. The acquisition of Hasten Biopharmaceuticals (SG) Pte. Ltd. further strengthened the company’s global commercialization capabilities and established a pan-Asia-Pacific commercialization platform. The platform provides a foundation for scaling the company’s proven commercialization capabilities from China across Asian markets, supporting the regional expansion of both existing and future products. Meanwhile, CBC Group and the company’s Directors have collectively purchased 5.163 million shares since December 2025, with the transactions totaling more than HK$172.5 million, demonstrating their confidence in the company’s strategic direction and long-term prospects. Overall, Everest Medicines is gradually developing a growth model built on the commercialization of core products, portfolio expansion through BD, a pipeline of innovative assets generated through in-house R&D, and international expansion through global partnerships and its pan-Asia-Pacific platform. As the company enters its new phase, the coordinated strengthening of its capabilities in innovation resource integration, commercialization, and global development is expected to provide an important foundation for future growth.
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