Global Animal Model Market - Size, Share, Trends, and Forecast, 2021-2031F | 8.53% CAGR Opportunity Fueled by Humanized Models and CRO Outsourcing

Dublin, Oct. 14, 2026 -- "Animal Model Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2021-2031F" has been added to ResearchAndMarkets.com's offering.

Global Animal Model Market to Reach USD 3.22 Billion by 2031

The Global Animal Model Market is projected to increase from USD 1.97 billion in 2025 to USD 3.22 billion by 2031, registering a compound annual growth rate of 8.53%. Demand for rodents, primates, zebrafish, and other non-human research models continues to rise as pharmaceutical companies, biotechnology firms, academic institutions, and Contract Research Organizations (CROs) expand preclinical drug development and biomedical research activities.

Market growth is supported by the increasing prevalence of chronic and infectious diseases, which has intensified the need for reliable toxicology, efficacy, and safety testing. Regulatory requirements for comprehensive preclinical assessments before human clinical trials also sustain demand for animal models across drug discovery and therapeutic development programs.

Market Drivers: Rising pharmaceutical and biotechnology research and development (R&D) expenditure is a primary driver of the animal model market. Global drugmakers invested nearly USD 288 billion in R&D during 2024, according to BioSpace data published in May 2025. This investment supports a consistent requirement for in vivo systems used to evaluate novel drugs, vaccines, biologics, and other medical interventions.

Government funding provides additional support for academic and public biomedical research. The National Institutes of Health (NIH) received USD 46.995 billion for fiscal year 2025, according to Congress.gov data published in December 2025. Such funding enables continued research involving genetically modified and disease-specific models, particularly in oncology, immunology, infectious disease, and translational medicine.

Specialized research providers are also benefiting from sustained demand. Charles River Laboratories reported total revenue of USD 4.05 billion in 2024, while its Research Models and Services segment generated USD 829.4 million. These results highlight the importance of external providers offering model production, breeding, management, and preclinical research services.

Market Challenges: Stringent international animal welfare regulations and intensifying ethical scrutiny remain significant constraints. Regulatory frameworks increasingly emphasize the '3Rs' principles - Replacement, Reduction, and Refinement - encouraging researchers to reduce live animal use and adopt alternative testing technologies when appropriate.

Compliance with animal welfare standards can increase operating expenses and extend study approval timelines. Pharmaceutical and biotechnology organizations may consequently allocate more funding to regulatory compliance, organ-on-chip platforms, computational modeling, cell-based assays, and other non-animal methods. According to the UK Bioscience Sector Coalition, scientific procedures involving animals in the UK had declined to approximately 77% of 2019 levels by 2025, demonstrating the impact of regulatory and ethical pressures on model usage.

Market Trends: Humanized immune system models are gaining importance because they can improve the clinical relevance of preclinical research, especially in immuno-oncology and antibody development. These models support the evaluation of therapeutic candidates in biological systems containing functional human immune components. Biocytogen completed approximately 200 therapeutic antibody co-development and licensing agreements involving its RenMice humanized model platforms by the end of 2024, according to a June 2025 company announcement.

Outsourcing animal model generation and management to CROs is another major trend. The complexity and cost of maintaining sophisticated genetic lines in-house are encouraging drug developers to work with specialized service providers. Outsourcing allows companies to access technical expertise, reduce fixed infrastructure requirements, and align research spending with project demand.

Key Market Players:

• Charles River Laboratories International Inc.
• The Jackson Laboratory
• Taconic Biosciences, Inc.
• Janvier Labs S.A.S.
• HBM Holdings Limited
• Crown Bioscience Inc.
• Inotiv Inc.
• Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
• BioSpherix, Ltd

Report Scope: The Global Animal Model Market report evaluates market size, growth opportunities, industry trends, challenges, and demand across animal types, applications, distribution channels, and regions.

Animal Model Market, by Animal Type:

• Mice
• Rat
• Guinea Pigs
• Rabbits
• Hamsters
• Others

Animal Model Market, by Application:

• Cancer
• Immunological Disease
• Infectious Disease
• Others

Animal Model Market, by Distribution Channel:

• Pharmaceutical & Biotechnology Companies
• Academic Research Institute
• Contract Research Organization

Animal Model Market, by Region:

• North America
• Europe
• Asia Pacific
• South America
• Middle East & Africa

Report Attribute	Details
No. of Pages	185
Forecast Period	2025 - 2031
Estimated Market Value (USD) in 2025	$1.97 Billion
Forecasted Market Value (USD) by 2031	$3.22 Billion
Compound Annual Growth Rate	8.5%
Regions Covered	Global

For more information about this report visit https://www.researchandmarkets.com/r/h9v4t0

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